On his birthday Mega Man really wishes to become human. So he is ready to pass the Three Challenges to accomplish humanity.

The N Team struggle to find weapons with enough power to defeat the magic of the Sacred Treasures.

Mother Brain challenges the N-Team to an athletic competition on Mount Icarus, thus distracting them from stopping her from finding the Three Sacred Treasures.

While the N team tries to get Simon's memory back, Mother Brain gets King Hippo and Eggplant Wizard to brainwash him into thinking he's an N-Team hunter. Later Simon believes he is Donkey Kong Jr.

Kevin, Lana, Simon, and Duke go to the Mirror World to rescue the princess' father, King Charles. In the mean time their opposites are on a journey to their world.

Mother Brain makes a discovery that Kevin isn't very good at the Bayou Billy video game. So she sets a trap to lure him into Bayouland.

Kevin Keene and his dog Duke have been transported to Video Land and asked to help defeat Mother Brain. After Princess Lana is kidnapped Kevin and his video game companions (Mega-Man, Kid Icarus, and Simon Belmont) have to work together to save her.

Focuses on key players in the history of the professional baseball team known as the St. Louis Browns for fifty-two years before moving to Baltimore.