Drew opens on the eve of Ethan Miller's freshman year of high school in a brand new town. He's finally sporting a haircut he doesn't hate, has grown two inches since middle school, and can't wait to try out for the soccer team. At last, everything is looking up in life. Until the next morning. When Ethan awakens as a girl. Ethan is a Changer, a little known, ancient race of humans who live out each of their four years of high school as a different...

When Ethan awakens to his sophomore year of high school in the body of Oryon, an African American skateboarder, he must determine where he fits in the social structure at school and the status of his friendship with Audrey.