Fifteen-year-old Josh has chosen to side neither with his twin sister Sophie nor with the Alchemyst, Nicholas Flamel, but rather to fight alongside Dr. John Dee and the mysterious Virginia Dare, while the immortal Machiavelli and Billy the Kid follow the Elders' plans to set loose the monsters of Alcatraz on San Francisco and trigger the end of the humani race.

When alchemist Sydney is ordered into hiding to protect the life of Moroi princess Jill Dragomir, the last place she expects to be sent is a human private school in Palm Springs, California. But at their new school, the drama is only just beginning.

Seventeen-year-old Donna Underwood is considered a freak, cursed by the magical heritage that destroyed her alchemist parents, but when vicious wood elves abduct her best friend Navin, Donna must betray all her parents fought for and join the battle between the humans and the fey.

With the twins of prophecy split, Nicholas Flamel near death, and John Dee in possession of the swords of power, Danu Talis has yet to fall and the future of the human race lies in the balance.

With Scatty, Joan of Arc, Saint Germain, Palamedes, and Shakespeare all in Danu Talis, Sophie is on her own with the ever-weakening Nicholas and Perenelle Flamel. She must depend on Niten to help her find an immortal to teach her Earth Magic. The surprise is that she will find her teacher in the most ordinary of places.